The signal transducers and activators of transcription (STAT) factors function as downstream
effectors of cytokine and growth factor receptor signaling. Compared with normal cells and …

The failure of the immune system to provide protection against tumour cells is an important
immunological problem. It is now evident that inadequate function of the host immune …

Constitutive activation of signal transducer and activator of transcription (STAT) proteins has
been detected in a wide variety of human primary tumor specimens and tumor cell lines …

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies, and is also the
fourth most common cancer worldwide with around 700,000 new cases each year …

Abstract Signal Transducers and Activators of Transcription (STATs) are a family of
cytoplasmic proteins with roles as signal messengers and transcription factors that …

Altered growth factor responses in phospho-protein-driven signaling networks are crucial to
cancer cell survival and pathology. Profiles of cancer cell signaling networks might therefore …

Signal transducers and activators of transcription (STATs) were identified originally as key
components of cytokine signaling pathways. More recently, constitutive activation of STAT …

Cells from multicellular organisms are dependent upon exogenous signals for survival,
growth, and proliferation. The relationship among these three processes was examined …

Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
signaling proteins that participates in normal cellular responses to cytokines and growth …

Granulocyte colony-stimulating factor (G-CSF) was reported to induce myocardial
regeneration by promoting mobilization of bone marrow stem cells to the injured heart after …