Cathelicidins are small, cationic, antimicrobial peptides found in humans and other species,
including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some …

Polymorphonuclear neutrophils are the first cells recruited to inflammatory sites and form the
earliest line of defense against invading microorganisms. Neutrophil elastase, proteinase 3 …

Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …

Recent in vivo studies indicate that mesenchymal stem cells (MSCs) may have beneficial
effects in the treatment of sepsis induced by bacterial infection. Administration of MSCs in …

SARS-CoV-2 is a respiratory pathogen and primarily infects the airway epithelium. As our
knowledge about innate immune factors of the respiratory tract against SARS-CoV-2 is …

In 1981, R. Edgar Hope-Simpson proposed that a 'seasonal stimulus' intimately associated
with solar radiation explained the remarkable seasonality of epidemic influenza. Solar …

The airways mucus gel performs a critical function in defending the respiratory tract against
pathogenic and environmental challenges. In normal physiology, the secreted mucins, in …

Introduction Alzheimer's disease (AD) is characterized by neurotoxic immuno‐inflammation
concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in …

Inhaled air is contaminated with pathogens and particulates that may deposit in the airways
and damage the host. In response to these invaders, the airway epithelium has developed …

The advent of Cystic fibrosis transmembrane receptor (CFTR) modulators in 2012 was a
critical event in the history of cystic fibrosis (CF) treatment. Unlike traditional therapies that …