Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterized by the
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …

Parkinson's disease is a progressive neurodegenerative condition associated with the
deposition of aggregated α-synuclein. Insights into the pathogenesis of Parkinson's disease …

Mutations in the human ATP13A2 (PARK9), a lysosomal ATPase, cause Kufor-Rakeb
Syndrome, an early-onset form of Parkinson's disease (PD). Here, we demonstrate that …

Parkinson's disease (PD) is a multifactorial disorder involving a complex interplay between a
variety of genetic and environmental factors. In this scenario, mitochondrial impairment and …

Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …

Human cells are exposed to numerous exogenous and endogenous insults every day.
Unlike other molecules, DNA cannot be replaced by resynthesis, hence damage to DNA can …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disease in middle-aged and elderly populations, whereas there is no cure for PD so far …

Parkinson's disease (PD) is a devastating disease associated with accumulation of α-
synuclein (α-Syn) within dopaminergic neurons, leading to neuronal death. PD is …

Disruption of the gut‐brain axis in Parkinson's disease (PD) may lead to motor symptoms
and PD pathogenesis. Recently, the neuroprotective potential of different PPARδ‐agonists …

Parkinson's disease (PD) is a common movement disorder associated with the degeneration
of dopaminergic neurons in the substantia nigra pars compacta. Mutations in the PD …