Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review

B Peltanova, M Raudenska, M Masarik - Molecular cancer, 2019 - Springer
The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …

Prognostic value of the immunohistochemical detection of cancer‐associated fibroblasts in oral cancer: A systematic review and meta‐analysis

MR Dourado, ENS Guerra, T Salo… - Journal of oral …, 2018 - Wiley Online Library
Aim To perform a meta‐analysis to assess whether the presence of cancer‐associated
fibroblasts (CAF) is a prognostic marker of oral squamous cell carcinomas (OSCC). Methods …

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

CM Carnielli, CCS Macedo, T De Rossi… - Nature …, 2018 - nature.com
Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological
and molecular characteristics limiting the standard tumor− node− metastasis prognosis …

Treatment of Chronic Kidney Disease with Extracellular Vesicles from Mesenchymal Stem Cells and CD133+ Expanded Cells: A Comparative Preclinical Analysis

DM Miyasaki, AC Senegaglia, SAB de Moura… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) is characterized by structural abnormalities and the
progressive loss of kidney function. Extracellular vesicles (EVs) from human umbilical cord …

New insights into the role of the oral leukoplakia microenvironment in malignant transformation

WA González-Arriagada, G Canedo-Marroquin… - Frontiers in Oral …, 2024 - frontiersin.org
Oral leukoplakia is the most frequent and potentially malignant lesion of the oral cavity.
Although dysplasia grading remains the main factor for risk assessment, challenges persist …

PDGFRβ is a novel marker of stromal activation in oral squamous cell carcinomas

VK Kartha, L Stawski, R Han, P Haines, G Gallagher… - PLoS …, 2016 - journals.plos.org
Carcinoma associated fibroblasts (CAFs) form the main constituents of tumor stroma and
play an important role in tumor growth and invasion. The presence of CAFs is a strong …

Myofibroblasts in oral potentially malignant disorders: Is it related to malignant transformation?

RD Coletta, T Salo - Oral diseases, 2018 - Wiley Online Library
In oral cancer, acquisition of α‐smooth muscle actin (α‐SMA)‐positive fibroblasts, known as
myofibroblasts or carcinoma‐associated fibroblasts (CAF), is an important event for …

[HTML][HTML] Mesenchymal stem cells accelerate the remodeling of bladder VX2 tumor interstitial microenvironment by TGFβ1-Smad pathway

Q Yang, J Chen, Y Zhu, Z Xu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Background: Mesenchymal stem cells (MSCs) have been proved to be able to differentiate
into cells that are conducive to tumor growth and invasion. The mechanism is not clear. This …

Prevalence of human papillomavirus type 16 in persistent oral lesions arising in patients with tobacco, areca nut, and alcohol habits

S Khowal, SK Jain, S Wajid - Oral Science International, 2019 - Wiley Online Library
Background and purpose Human papillomavirus (HPV) has been shown to be associated
with oral malignancies. The purpose of this study was to detect HPV and a high‐risk type …

Role of fibrotic cancer stroma in rectal carcinoma: An immunomorphological assessment

N Kaur, S Zaheer, P Sharma, V Rohilla… - Clinical Cancer …, 2021 - ccij-online.org
Background: The aim of the study is to evaluate the role of fibrotic cancer stromal response
and tumor budding in ectal adenocarcinoma development and progression. Materials and …