Predicting glycan structure from tandem mass spectrometry via deep learning

J Urban, C Jin, KA Thomsson, NG Karlsson, CM Ives… - Nature …, 2024 - nature.com
Glycans constitute the most complicated post-translational modification, modulating protein
activity in health and disease. However, structural annotation from tandem mass …

Mammalian milk glycomes: Connecting the dots between evolutionary conservation and biosynthetic pathways

L Thomès, V Karlsson, J Lundstrøm, D Bojar - Cell Reports, 2023 - cell.com
Milk oligosaccharides (MOs) are among the most abundant constituents of breast milk and
are essential for health and development. Biosynthesized from monosaccharides into …

GlycoDraw: a python implementation for generating high-quality glycan figures

J Lundstrøm, J Urban, L Thomès, D Bojar - Glycobiology, 2023 - academic.oup.com
Glycans are essential to all scales of biology, with their intricate structures being crucial for
their biological functions. The structural complexity of glycans is communicated through …

Compositional data analysis enables statistical rigor in comparative glycomics

AR Bennett, J Lundstrøm, S Chatterjee… - Nature …, 2025 - nature.com
Comparative glycomics data are compositional data, where measured glycans are parts of a
whole, indicated by relative abundances. Applying traditional statistical analyses to these …

[HTML][HTML] The evolving world of milk oligosaccharides: Biochemical diversity understood by computational advances

J Lundstrøm, D Bojar - Carbohydrate Research, 2024 - Elsevier
Milk oligosaccharides, complex carbohydrates unique to mammalian milk, play crucial roles
in infant nutrition and immune development. This review explores their biochemical diversity …

Navigating the maze of mass spectra: a machine-learning guide to identifying diagnostic ions in O-glycan analysis

J Urban, R Joeres, L Thomès, KA Thomsson… - Analytical and …, 2024 - Springer
Structural details of oligosaccharides, or glycans, often carry biological relevance, which is
why they are typically elucidated using tandem mass spectrometry. Common approaches to …

Ratios in Disguise, Truths Arise: Glycomics Meets Compositional Data Analysis

AR Bennett, J Lundstrøm, S Chatterjee… - bioRxiv, 2024 - biorxiv.org
Comparative glycomics data are an instance of compositional data defined by the Aitchison
simplex, where measured glycans are parts of a whole, indicated by relative abundances …

[HTML][HTML] The key to co-evolution between humans and colonic bifidobacteria; the acquisitions of type 1 oligosaccharides abundance in breast milk as well as type 1 …

T Urashima, K Fukuda, M Kitaoka, S Fushinobu… - Glycoforum, 2024 - glycoforum.gr.jp
After graduation from Tohoku University (Doctor of Agriculture) in 1986, he started his
professional career by studying milk oligosaccharides at Obihiro University. In 1991, he …

Explorando o papel do 2'-Fucosilactose (2'FL) na nutrição infantil: benefícios, identificação e produção

E da Silva Gomes… - …, 2024 - ojs.observatoriolatinoamericano …
Resumo O 2'-fucosilactose (2'FL) é um oligossacarídeo presente em abundância no leite
humano, reconhecido por seus múltiplos benefícios à saúde infantil. Este artigo de revisão …

[HTML][HTML] ヒトービフィズス菌共生進化の鍵, ヒト固有のタイプ1 型ミルクオリゴ糖優先性への進化とヒト腸内定着性ビフィズス菌によるタイプ1 型糖鎖代謝酵素の獲得

浦島匡, 福田健二, 北岡本光, 伏信進矢, 片山高嶺 - Glycoforum, 2024 - glycoforum.gr.jp
1986 年東北大学博士取得後, 帯広畜産大学畜産学部酪農化学教室に赴任,
ミルクオリゴ糖の研究に従事. 1991 年文部省在外研究員としてシドニー大学生化学部門にて, Dr …