Synaptic neurexin complexes: a molecular code for the logic of neural circuits

TC Südhof - Cell, 2017 - cell.com
Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …

Neurotoxins affecting neuroexocytosis

G Schiavo, M Matteoli… - Physiological reviews, 2000 - journals.physiology.org
Nerve terminals are specific sites of action of a very large number of toxins produced by
many different organisms. The mechanism of action of three groups of presynaptic …

[HTML][HTML] FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development

ML O'Sullivan, J de Wit, JN Savas, D Comoletti… - Neuron, 2012 - cell.com
Latrophilins (LPHNs) are a small family of G protein-coupled receptors known to mediate the
massive synaptic exocytosis caused by the black widow spider venom α-latrotoxin, but their …

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

M Arcos-Burgos, M Jain, MT Acosta, S Shively… - Molecular …, 2010 - nature.com
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) has a very high heritability (0.8),
suggesting that about 80% of phenotypic variance is due to genetic factors. We used the …

[图书][B] Applications of group-theoretical methods in hydrodynamics

VK Andreev, OV Kaptsov, VV Pukhnachev… - 1998 - books.google.com
It was long ago that group analysis of differential equations became a powerful tool for
studying nonlinear equations and boundary value problems. This analysis was especially …

Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology

T Lala, RA Hall - Physiological Reviews, 2022 - journals.physiology.org
Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …

CASK and protein 4.1 support F-actin nucleation on neurexins

T Biederer, TC Südhof - Journal of Biological Chemistry, 2001 - ASBMB
Rearrangements of the actin cytoskeleton are involved in a variety of cellular processes from
locomotion of cells to morphological alterations of the cell surface. One important question is …

α-Latrotoxin and its receptors: neurexins and CIRL/latrophilins

TC Südhof - Annual review of neuroscience, 2001 - annualreviews.org
▪ Abstract α-Latrotoxin, a potent neurotoxin from black widow spider venom, triggers synaptic
vesicle exocytosis from presynaptic nerve terminals. α-Latrotoxin is a large protein toxin (120 …

Adhesion G protein-coupled receptors: signaling, pharmacology, and mechanisms of activation

KJ Paavola, RA Hall - Molecular pharmacology, 2012 - ASPET
The adhesion G protein-coupled receptors (GPCRs) are a distinct family of more than 30
receptors in vertebrate genomes. These receptors have been shown to play pivotal roles in …

Contribution of LPHN3 to the genetic susceptibility to ADHD in adulthood: a replication study

ÁM Ribases, JA Ramos‐Quiroga… - Genes, Brain and …, 2011 - Wiley Online Library
Attention‐deficit/hyperactivity disorder (ADHD) is a common and highly heritable
developmental disorder characterized by a persistent impairing pattern of inattention and/or …