Impact of endemic infections on HIV susceptibility in sub-Saharan Africa
Human immunodeficiency virus (HIV) remains a leading cause of global morbidity with the
highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood …
highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood …
Effects of Schistosoma haematobium infection and treatment on the systemic and mucosal immune phenotype, gene expression and microbiome: A systematic review
AM Mertelsmann, SF Bowers, D Wright… - PLOS Neglected …, 2024 - journals.plos.org
Background Urogenital schistosomiasis caused by Schistosoma haematobium affects
approximately 110 million people globally, with the majority of cases in low-and middle …
approximately 110 million people globally, with the majority of cases in low-and middle …
Dynamics of host immune response development during Schistosoma mansoni infection
AH Costain, AT Phythian-Adams… - Frontiers in …, 2022 - frontiersin.org
Schistosomiasis is a disease of global significance, with severity and pathology directly
related to how the host responds to infection. The immunological narrative of …
related to how the host responds to infection. The immunological narrative of …
Cervicovaginal immune activation in Zambian women with female genital schistosomiasis
AS Sturt, EL Webb, C Patterson, CR Phiri… - Frontiers in …, 2021 - frontiersin.org
HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high
HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female …
HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female …
[HTML][HTML] Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways
Schistosoma mansoni (Sm) infection has been linked with an increased risk of HIV
acquisition in women. Therefore, defining the mechanism (s) by which Sm alters HIV …
acquisition in women. Therefore, defining the mechanism (s) by which Sm alters HIV …
Transcriptome analysis of peripheral blood of Schistosoma mansoni infected children from the Albert Nile region in Uganda reveals genes implicated in fibrosis …
Over 290 million people are infected by schistosomes worldwide. Schistosomiasis control
efforts focus on mass drug treatment with praziquantel (PZQ), a drug that kills the adult worm …
efforts focus on mass drug treatment with praziquantel (PZQ), a drug that kills the adult worm …
MicroRNA-Transcription factor regulatory networks in the early strobilar development of Echinococcus granulosus protoscoleces
Background Echinococcus granulosus sensu lato has a complex developmental biology
with a variety of factors relating to both intermediate and final hosts. To achieve maximum …
with a variety of factors relating to both intermediate and final hosts. To achieve maximum …
Altered cervical mucosal gene expression and lower interleukin 15 levels in women with Schistosoma haematobium infection but not in women with Schistosoma …
KM Dupnik, MH Lee, P Mishra, MJ Reust… - The Journal of …, 2019 - academic.oup.com
Background Schistosomiasis increases the risk of human immunodeficiency virus (HIV)
acquisition in women by mechanisms that are incompletely defined. Our objective was to …
acquisition in women by mechanisms that are incompletely defined. Our objective was to …
[HTML][HTML] Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania
K Pham, GS Mtalitinya, C Aristide, EA Airewele… - Acta tropica, 2023 - Elsevier
Schistosomes infect over 200 million people worldwide, but few studies have characterized
the effects of Schistosoma mansoni infection and effective treatment on the lower …
the effects of Schistosoma mansoni infection and effective treatment on the lower …
Sex as a biological variable in HIV-1 and schistosome co-infection
JK Maganga, K Pham, JM Changalucha, JA Downs - The Lancet HIV, 2025 - thelancet.com
The sex of people living with HIV-1 infection, schistosome infection, or both, is a fundamental
determinant of their clinical outcomes and of how these two infections interact in the host …
determinant of their clinical outcomes and of how these two infections interact in the host …