An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infections through NPC1 inhibitor

I Ahmad, SN Fatemi, M Ghaheri, A Rezvani… - Cell Communication and …, 2023 - Springer
Viruses communicate with their hosts through interactions with proteins, lipids, and
carbohydrate moieties on the plasma membrane (PM), often resulting in viral absorption via …

Binding free energy of several sterols to the N‐terminal domain of Niemann‐Pick C1‐like 1 protein due to mutation: Molecular dynamics study

HJ Yoon, Y Lee, J Jeong, S Jang… - Journal of the …, 2023 - Wiley Online Library
Abstract The membrane protein Niemann‐Pick type C1‐like 1 (NPC1L1) plays a central role
in the absorption of cholesterol in the small intestine. Other sterols, notably vitamin E and …