With the advent of long-read sequencing, previously unresolvable genomic elements are
being revisited in an effort to generate fully complete reference genomes. One such element …

The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal
RNA (rRNA) genes. They serve as the site of rRNA synthesis and processing, and ribosome …

Many trace metal pollutants in surface water, the atmosphere, and soil are carcinogenic, and
ribosome biogenesis plays an important role in the carcinogenicity of heavy metals …

The genes that encode ribosomal RNAs are present in several hundred copies in most
eukaryotes. These vast arrays of repetitive ribosomal DNA (rDNA) have been implicated not …

With hundreds of copies of rDNA, it is unknown whether they possess sequence variations
that form different types of ribosomes. Here, we developed an algorithm for long-read variant …

Abstract Hexavalent chromium [Cr (Ⅵ)] has extensive applications in industries, and long-
term occupational exposure to Cr (Ⅵ) may lead to lung carcinoma and other cancers. While …

Herein, we made 3D MXene-AuNPs by in situ growth of gold nanoparticles (AuNPs) on the
surface of MXene by chemical reduction method, and then introduced three sulfhydryl (-SH) …

The nucleolus harbors the machinery necessary to produce new ribosomes which are
critical for protein synthesis. Nucleolar size, shape, and density are highly dynamic and can …

The past thirty years have seen a surge in interest in pathophysiological roles of
mitochondria, and the accurate quantification of mitochondrial DNA copy number (mCN) in …

There are several sources of heavy metal exposures whether occupational or
environmental. These are connected both with the existence of natural reservoirs of metal …