The modern ribosome was largely formed at the time of the last common ancestor, LUCA.
Hence its earliest origins likely lie in the RNA world. Central to its development were RNAs …

The ribosome is a prototypical assembly that can be used to establish general principles
and techniques for the study of biological molecular machines. Motivated by the fact that the …

In this paper we present a study of the peptide bond formation reaction catalyzed by
ribosome. Different mechanistic proposals have been explored by means of Free Energy …

To study the conversion from a meso form to a racemic form of tetrahydrofurantetracarboxylic
acid (H4L), seven novel coordination polymers were synthesized by the hydrothermal …

The relationship of molecular chirality and biology is intriguing. Our curiosity prompts the
question as to why diverse natural biological molecules are overwhelmingly dissymmetric. Is …

Ribosomes transform the genetic information encoded within genes into proteins. In recent
years, there has been much progress in the study of this complex molecular machine, but …

Chirality is present at all levels of structural hierarchy of protein and plays a significant role in
protein biosynthesis. The macromolecules involved in protein biosynthesis such as …

Chirality transformation is a basic, attractive, and important strategy for obtaining
enantioenriched products with desired chiral elements. The reported chirality conversion …

The peptidyl transfer reaction on the large ribosomal subunit depends on the protonation
state of the amine nucleophile and exhibits a large kinetic solvent isotope effect (KSIE∼ 8) …

Although chiral discrimination in biological systems is overwhelmingly present, its molecular
mechanism remained a puzzle. Why the basic blocks of life like l-amino acid and d-sugar …