The use of precision diagnostics for monogenic diabetes: a systematic review and expert opinion

R Murphy, K Colclough, TI Pollin, JM Ikle… - Communications …, 2023 - nature.com
Background Monogenic diabetes presents opportunities for precision medicine but is
underdiagnosed. This review systematically assessed the evidence for (1) clinical criteria …

[PDF][PDF] Atypical Diabetes: What Have We Learned and What Does the Future Hold?

SI Stone, A Balasubramanyam, JE Posey - Diabetes Care, 2024 - Am Diabetes Assoc
As our understanding of the pathophysiology of diabetes evolves, we increasingly recognize
that many patients may have a form of diabetes that does not neatly fit with a diagnosis of …

[HTML][HTML] A Systematic Review of the use of Precision Diagnostics in Monogenic Diabetes

R Murphy, K Colclough, TI Pollin, JM Ikle, P Svalastoga… - medRxiv, 2023 - ncbi.nlm.nih.gov
Monogenic forms of diabetes present opportunities for precision medicine as identification of
the underlying genetic cause has implications for treatment and prognosis. However …

[HTML][HTML] Monogenic Forms of Diabetes

MV Salguero, M Arosemena, T Pollin… - Diabetes in America …, 2023 - ncbi.nlm.nih.gov
Monogenic diabetes is a term used to describe a group of single-gene causes of diabetes.
Traditional nomenclature has focused on the types of diabetes known as MODY, defined as …

Molecular mechanisms of β-cell dysfunction and death in monogenic forms of diabetes

LS Caballero, V Gorgogietas, MN Arroyo… - International Review of …, 2021 - Elsevier
Monogenetic forms of diabetes represent 1%–5% of all diabetes cases and are caused by
mutations in a single gene. These mutations, that affect genes involved in pancreatic β-cell …

Genetic counseling in diabetes mellitus: A practice resource of the National Society of Genetic Counselors

KA Maloney, E Mizerik, RH King… - Journal of Genetic …, 2023 - Wiley Online Library
Diabetes mellitus is a group of diseases characterized by hyperglycemia and its
consequences, affecting over 34 million individuals in the United States and 422 million …

Diabetic Nephropathy, Retinopathy, and Functional Hypogonadism in a Patient with MODY10: A Case Report

R Ruiz-Urbaez, MV Villagómez-Estrada, C Reyes-Silva… - Medicina, 2024 - mdpi.com
(1) Background and objectives: Maturity-onset diabetes of the young (MODY) is a group of
diabetes caused by gene defects related to insulin secretion. MODY1, MODY2, and MODY3 …

[HTML][HTML] Implementing genetic testing in diabetes: Knowledge, perceptions of healthcare professionals, and barriers in a developing country

WO Balogun, R Naylor, BO Adedokun… - Population …, 2024 - ncbi.nlm.nih.gov
METHODS A cross-sectional survey was conducted among doctors and nurses in three
levels of public and private healthcare institutions in Ibadan, Nigeria, from December 2018 …

Diagnosis of hepatic nuclear factor 1A monogenic diabetes mellitus (HNF1A-MODY) impacts antihyperglycemic treatment

WJ Schnedl, SJ Holasek, M Schenk, D Enko… - Wiener klinische …, 2021 - Springer
Monogenic mutations of the hepatocyte nuclear factor 1 homeobox A maturity onset
diabetes of the young (HNF1A-MODY) is characterized by early onset, typically before the …