Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Cholangiocarcinoma—novel biological insights and therapeutic strategies

SI Ilyas, S Affo, L Goyal, A Lamarca… - Nature Reviews …, 2023 - nature.com
In the past 5 years, important advances have been made in the scientific understanding and
clinical management of cholangiocarcinoma (CCA). The cellular immune landscape of CCA …

Classical and noncanonical functions of miRNAs in cancers

MP Dragomir, E Knutsen, GA Calin - Trends in Genetics, 2022 - cell.com
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

miRNAs orchestration of gallbladder cancer-Particular emphasis on diagnosis, progression and drug resistance

RK Shahin, MA Elkady, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …

MicroRNAs in liver disease

G Szabo, S Bala - Nature reviews Gastroenterology & hepatology, 2013 - nature.com
Small, noncoding microRNAs (miRNAs) regulate diverse biological functions in the liver and
increasing evidence suggests that they have a role in liver pathology. This Review …

[HTML][HTML] Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?

S Kumar, PH Reddy - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss, multiple cognitive abnormalities and intellectual impairments. Currently, there …

Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

[HTML][HTML] Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer …

A Bakrania, N Joshi, X Zhao, G Zheng, M Bhat - Pharmacological research, 2023 - Elsevier
Liver cancers are the fourth leading cause of cancer-related mortality worldwide. In the past
decade, breakthroughs in the field of artificial intelligence (AI) have inspired development of …

Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

G Zhuang, X Wu, Z Jiang, I Kasman, J Yao… - The EMBO …, 2012 - embopress.org
Angiogenesis plays a crucial role during tumorigenesis and much progress has been
recently made in elucidating the role of VEGF and other growth factors in the regulation of …

Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer

A Allegra, A Alonci, S Campo… - International …, 2012 - spandidos-publications.com
MicroRNAs (miRNAs) are small non-coding, endogenous, single-stranded RNAs. MiRNAs
have been implicated in different areas such as the immune response, neural development …