Importance Results of clinical trials can only represent included participants, and many
neonatal trials fail due to insufficient participation. Infants not included in research may differ …

In persistent pulmonary hypertension of the newborn (PPHN), the ratio of pulmonary
vascular resistance to systemic vascular resistance is increased. Extrapulmonary shunts …

Objective To assess the impact of milrinone administration on time spent on nitric oxide
(iNO) in infants with acute pulmonary hypertension (aPH). We hypothesized that intravenous …

Inotrope/vasopressors are commonly used in the neonatal intensive care unit (NICU) but
with wide variations in practice regarding indications, duration, and dosing 1, 2 (Table 1) …

Objective To determine whether restricting the use of inotrope after diagnosis of low blood
pressure (BP) in the first 72 hours of life affects survival without significant brain injury at 36 …

For almost half a century, inotropes have been administered to preterm infants with the
ultimate goal of increasing their blood pressure. A number of trials, the majority of which …

Persistent pulmonary hypertension of the newborn (PPHN) is an essential cause for hypoxic
respiratory failure with significant morbidity and mortality in term and near-term neonates …

Clamping and cutting the umbilical cord at birth occurs for each of the 140 million neonates
born annually. 1 The benefits of delayed cord clamping (DCC; waiting∼ 1–2 min before …

Abstract The Eunice Kennedy Shriver National Institute of Child Health and Human
Development (NICHD) Neonatal Research Network (NRN) has been a leader in neonatal …

Anti-hypotensive treatment, which includes dopamine, dobutamine, epinephrine,
norepinephrine, milrinone, vasopressin, terlipressin, levosimendan, and glucocorticoids, is a …