The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …

The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …

Seizures result from hypersynchronous, abnormal firing of neuronal populations and are the
primary clinical symptom of the epilepsies. Brain tissue from animal models and patients …

At present, it is necessary to identify specific biochemical, molecular, and genetic markers
that can reliably aid in screening digestive cancer and correlate with the degree of disease …

Protein turnover, the net result of protein synthesis and degradation, enables cells to
remodel their proteomes in response to internal and external cues. Previously, we analyzed …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

Epilepsy is a common and serious neurological disorder characterised by recurrent
spontaneous seizures. Frontline pharmacotherapy includes small-molecule antiseizure …

Homeostatic synaptic plasticity is a process by which neurons adjust their synaptic strength
to compensate for perturbations in neuronal activity. Whether the highly diverse synapses on …

Alzheimer's disease (AD) is a progressive neurological disease characterized by the loss of
cognitive function, confusion, and memory deficit. Accumulation of abnormal proteins …

It is crucial to understand the molecular mechanisms involved in epileptogenesis. This study
aims to investigate the role of lncRNA NEAT1, miR-129-5p and Notch signaling pathway in …