Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted …

M Liao, R Qin, W Huang, HP Zhu, F Peng… - Journal of Hematology & …, 2022 - Springer
Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Regulation of breast cancer metastasis signaling by miRNAs

BJ Petri, CM Klinge - Cancer and metastasis reviews, 2020 - Springer
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

[HTML][HTML] LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and …

PP Li, RG Li, YQ Huang, JP Lu, WJ Zhang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Genomic instability (GIN) is pivotal in regulating tumor drug resistance, which blocked the
treatment of triple negative breast cancer (TNBC). Although recent studies implied that non …

Roles of miRNA and IncRNA in triple-negative breast cancer

J Xu, K Wu, Q Jia, X Ding - Journal of Zhejiang University-science b, 2020 - Springer
Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast
cancer without effective targeted therapies, which makes its pathogenesis an important …

N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma

F Wang, Y Liao, M Zhang, Y Zhu, W Wang, H Cai… - Oncogene, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most abundant internal mRNA modification in
eukaryotes and plays an important role in tumorigenesis. However, the underlying …

Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression

X Zhang, L Wang, H Li, L Zhang, X Zheng… - Cell Death & …, 2020 - nature.com
Cancer progression including proliferation, metastasis, and chemoresistance has become a
serious hindrance to cancer therapy. This phenomenon mainly derives from the innate …

[HTML][HTML] A panel of eight microRNAs is a good predictive parameter for triple-negative breast cancer relapse

HC Hong, CH Chuang, WC Huang, SL Weng… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Triple-negative breast cancer (TNBC), which has the highest recurrence rate and
shortest survival time of all breast cancers, is in urgent need of a risk assessment method to …

[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway

Y Akkoc, D Gozuacik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …

MicroRNA dysregulation in cutaneous squamous cell carcinoma

N García-Sancha, R Corchado-Cobos… - International journal of …, 2019 - mdpi.com
Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …

[HTML][HTML] Roles of microRNAs in inflammatory bowel disease

HT Jung, JS Kim, KH Lee, K Tizaoui… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract that mainly affects young people. IBD is associated with various gastrointestinal …