Initial antimicrobial management of sepsis

MS Niederman, RM Baron, L Bouadma, T Calandra… - Critical care, 2021 - Springer
Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Ventilator-associated pneumonia: pathobiological heterogeneity and diagnostic challenges

F Howroyd, C Chacko, A MacDuff, N Gautam… - Nature …, 2024 - nature.com
Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …

Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis

SM Fernando, A Tran, W Cheng, M Klompas… - Intensive care …, 2020 - Springer
The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We …

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America …

AC Kalil, ML Metersky, M Klompas… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Matrix assisted laser desorption time of flight mass spectrometry (MALDI-TOF MS) in clinical microbiology

S Angeletti - Journal of microbiological methods, 2017 - Elsevier
The microbiological management of patients with suspected bacterial infection includes the
identification of the pathogen and the determination of the antibiotic susceptibility. These …

Diagnosing antimicrobial resistance

CAD Burnham, J Leeds, P Nordmann… - Nature Reviews …, 2017 - nature.com
Antimicrobial resistance constitutes a global burden and is one of the major threats to public
health. Although the emergence of resistant microorganisms is a natural phenomenon, the …

[HTML][HTML] Hospital-acquired pneumonia in ICU

M Leone, L Bouadma, B Bouhemad, O Brissaud… - … Critical Care & Pain …, 2018 - Elsevier
Abstract The French Society of Anesthesia and Intensive Care Medicine and the French
Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) …

Respiratory tract infections and laboratory diagnostic methods: a review with a focus on syndromic panel-based assays

A Calderaro, M Buttrini, B Farina, S Montecchini… - Microorganisms, 2022 - mdpi.com
Respiratory tract infections (RTIs) are the focus of developments in public health, given their
widespread distribution and the high morbidity and mortality rates reported worldwide. The …

High prevalence of multidrug-resistant nonfermenters in hospital-acquired pneumonia in Asia

DR Chung, JH Song, SH Kim… - American journal of …, 2011 - atsjournals.org
Rationale: Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP)
remain important causes of morbidity and mortality. Increasing antimicrobial resistance has …

Guidelines for the Evaluation and Treatment of Pneumonia

SN Grief, JK Loza - Primary Care: Clinics in Office …, 2018 - primarycare.theclinics.com
Pneumonia is a leading cause of hospitalization among both adults and children in the
United States, accounting for more than 800,000 hospitalizations and more than 400,000 …