Guideline-based management of asthma focuses on disease severity and choosing the
appropriate medical therapy to control symptoms and reduce the risk of exacerbations …

Background: Current guidelines recommend the use of a combination of inhaled β2 agonists
and anticholinergics, particularly for patients with acute severe or life threatening asthma in …

Asthma is a prevalent chronic disease of the respiratory system and acute asthma
exacerbations are among the most common causes of presentation to the emergency …

Background There are several treatment options for managing acute asthma exacerbations
(sustained worsening of symptoms that do not subside with regular treatment and require a …

About 10% of American children have asthma, and its prevalence, morbidity, and mortality
have been increasing. Asthma is an inflammatory disease with edema, bronchial …

The role for anticholinergic medications in acute asthma is not well-defined. Thus, the use of
therapy with anticholinergics and β 2-agonists, either simultaneously or in sequence, has …

As aerobic organisms, we are continuously and throughout our lifetime subjected to an
oxidizing atmosphere and, most often, to environmental threats. The lung is the internal …

Background Inhaled anticholinergics given in addition to β 2‐agonists are effective in
reducing hospital admissions in children presenting to the emergency department with a …

In the last 2 decades, anticholinergic agents have been generally regarded as the first-
choice bronchodilator therapy in the routine management of stable chronic obstructive …

Background A combination of ipratropium bromide (IB) and salbutamol is commonly used to
treat asthma in children and adolescents; however, there has been a lack of consistency in …