Hematological malignancies comprise a plethora of different neoplasms, such as leukemia,
lymphoma, and myeloma, plus a myriad of dysplasia, such as myelodysplastic syndromes or …

Colorectal cancer (CRC) is the third most common cancer and has the second highest
mortality rate among cancers. The development of CRC involves both genetic and …

CD8+ T cells kill target cells by releasing cytotoxic molecules and proinflammatory
cytokines, such as TNF and IFN‐γ. The magnitude and duration of cytokine production are …

Post-transcriptional regulation is a fundamental process in gene expression that has a role
in diverse cellular processes, including immune responses. A core concept underlying post …

T cells play key protective but also pathogenic roles in COVID-19. We studied the
expression of long non-coding RNAs (lncRNAs) in COVID-19 T-cell transcriptomes by …

T cell homeostasis, T cell differentiation, and T cell effector function rely on the constant fine‐
tuning of gene expression. To alter the T cell state, substantial remodeling of the proteome is …

Static gene expression programs have been extensively characterized in stem cells and
mature human cells. However, the dynamics of RNA isoform changes upon cell-state …

Potent T cell responses against infections and malignancies require a rapid yet tightly
regulated production of toxic effector molecules. Their production level is defined by post …

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are among the most abundantly
expressed RNA binding proteins in the cell and play major roles in all facets of RNA …

Autoimmune diseases are mainly characterized by the abnormal autoreactivity due to the
loss of tolerance to specific autoantigens, though multiple pathways associated with the …