Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis

W Liu, N Östberg, M Yalcinkaya, H Dou… - The Journal of …, 2022 - Am Soc Clin Investig
Elevated hematocrit is associated with cardiovascular risk; however, the causality and
mechanisms are unclear. The JAK2V617F (Jak2VF) mutation increases cardiovascular risk …

Erythrocytosis: Diagnosis and investigation

I Noumani, CN Harrison… - International Journal of …, 2024 - Wiley Online Library
An absolute erythrocytosis is present when the red cell mass is greater than 125% of the
predicted. This is suspected when the hemoglobin or hematocrit is above the normal range …

High platelet-to-lymphocyte ratio may differentiate polycythemia vera from secondary polycythemia

I Krečak, H Holik, M Morić Perić, I Zekanović… - Wiener klinische …, 2022 - Springer
Discriminating polycythemia vera (PV) from secondary polycythemia (SP) is crucial due to
the inherent risk of thrombosis in PV and different treatment approaches. The majority of PV …

Management of classical Philadelphia chromosome-negative myeloproliferative neoplasms in Asia: consensus of the Asian Myeloid Working Group

H Gill, GMK Leung, MGM Ooi, WZY Teo… - Clinical and …, 2023 - Springer
Myeloproliferative neoplasms (MPN) are a heterogeneous group of clonal hematopoietic
stem cell disorders characterized clinically by the proliferation of one or more hematopoietic …

Neutrophil‐to‐lymphocyte ratio and platelet‐to‐lymphocyte ratio as new possible minor criteria for diagnosis of polycythemia vera

MJ Kim, SS Kwon, YS Ji, MY Lee… - International Journal …, 2023 - Wiley Online Library
Introduction The role of inflammation in the pathophysiology of polycythemia vera (PV) is
important. The presence of JAK2 mutations is important in the diagnosis of PV, and serum …

The utility of testing erythropoietin level in polycythemia diagnosis

A Ismail, E Abdalla, A Aqel, A Fadul, A Ahmed… - …, 2023 - Taylor & Francis
Objectives: Polycythemia vera (PV) is classically thought to be associated with low
erythropoietin (EPO) levels. Here, we present a review of the utility of using EPO levels in …

Diagnostic performance of erythropoietin levels in polycythemia vera: Experience at a Comprehensive Cancer Center

D Davila-Gonzalez, A Barrios-Ruiz, E Fountain… - … Myeloma and Leukemia, 2021 - Elsevier
Introduction Considering the evolving diagnostic criteria of polycythemia vera (PV), we
analyzed the utility of serum erythropoietin (EPO) as a predictive marker for differentiating …

Revisiting Diagnostic performances of serum erythropoïetin level and JAK2 mutation for polycythemias: analysis of a cohort of 1090 patients with red cell mass …

N Maslah, O Ravdan, L Drevon… - British Journal of …, 2022 - Wiley Online Library
We assessed the diagnostic performances of erythropoietin and JAK2 mutations in 1,090
patients with suspected polycythemia who were referred for red cell mass (RCM) …

[PDF][PDF] Serum erythropoietin levels in 696 patients investigated for erythrocytosis with JAK2 mutation analysis

B Chin-Yee, I Cheong, M Matyashin, A Lazo-Langner… - 2022 - ir.lib.uwo.ca
1. Terpos E, Trougakos IP, Apostolakou F, et al. Age-dependent and gender-dependent
antibody responses against SARS-CoV-2 in health workers and octogenarians after …

Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience

Y Lee, SH Seo, J Kim, SA Kim, JY Lee, JO Lee… - Molecular Diagnosis & …, 2024 - Springer
Introduction Erythrocytosis is attributed to various clinical and molecular factors. Many cases
of JAK2-unmutated erythrocytosis remain undiagnosed. We investigated the characteristics …