The accumulation of the amyloid‐β peptides (Aβ) is central to the development of
Alzheimer's disease. The mechanism by which Aβ triggers a cascade of events that leads to …

Disruption of the neuronal membrane by toxic amyloid β oligomers is hypothesized to be the
major event associated with Alzheimer's disease's neurotoxicity. Misfolding of amyloid β is …

Noninvasive and label-free analysis of cell membranes at the nanoscale is essential to
comprehend vital cellular processes. However, conventional analytical tools generally fail to …

The microtubule associated protein, tau, is implicated in a multitude of neurodegenerative
disorders that are collectively termed as tauopathies. These disorders are characterized by …

The cell membrane is a fundamental biological structure, which is only 6–10 nm thick. It is
composed of hundreds of lipid types, which form small and dynamic lipid domains or rafts …

Amyloid-beta (Aβ1–42) aggregation triggers neurotoxicity and is linked to Alzheimer's
disease. Aβ1–42 oligomers, rather than extended fibrils, adhere to the cell membrane …

Amyloid-β peptide (Aβ) in serum is an effective biomarker for the early diagnosis of
Alzheimer's disease (AD). However, there are serious challenges to monitor subtle changes …

Neurodegeneration in Alzheimer's disease is associated with disruption of the neuronal cell
membrane by the amyloid β (Aβ) peptide. However, the disruption mechanism and the …

This short review describes our efforts to apply scanning tunneling microscopy and atomic
force microscopy to provide an understanding of the mechanism of phospholipid bilayer …

Misfolding, aggregation and accumulation of Amyloid-β peptides (Aβ) in neuronal tissue and
extracellular matrix are hallmark features of Alzheimer's disease (AD) pathology. Soluble Aβ …