Examination of tumor molecular characteristics by liquid biopsy is likely to greatly influence
personalized cancer patient management. Analysis of circulating tumor DNA (ctDNA) …

Simple Summary There is currently a lack of useful tests to detect microscopic residual
disease in patients who have undergone surgery to remove their bowel cancer. This inability …

Information about the kinetics of PCR reactions is encoded in the amplification curve.
However, in digital PCR (dPCR), this information is typically neglected by collapsing each …

Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan,
China and has since spread rapidly all over the world causing a global pandemic. While the …

Nucleic acids-based molecular diagnostic tools incorporating the CRISPR/Cas system are
being developed as rapid and sensitive methods for pathogen detection. However, most …

Heart failure is the final stage of various cardiovascular diseases and seriously threatens
human health. Increasing mediators have been found to be involved in the pathogenesis of …

Background: Chronic kidney disease (CKD) and cardiovascular diseases (CVD) often occur
concomitantly, and CKD is a major risk factor for cardiovascular mortality. Since some of the …

Monoclonal gammopathy of undetermined significance (MGUS) represents the pre-clinical
stage of Multiple Myeloma (MM) with the 5% of MGUS progresses to MM. Although the …

Organisms have developed different mechanisms to respond to stresses. However, the roles
of small ORF–encoded peptides (SEPs) in these regulatory systems remain elusive, which is …