Bioaffinity drug screening strategies have gained popularity in preclinical and clinical drug
discovery for natural products, small molecules and antibodies owing to their superior …

DNA-encoded library (DEL) technology is a powerful platform for the efficient identification of
novel chemical matter in the early drug discovery process enabled by parallel screening of …

Identifying biologically active ligands for membrane proteins is an important task in chemical
biology. We report an approach to directly identify small molecule agonists against …

DNA-encoded library (DEL) has proven to be a powerful tool that utilizes combinatorially
constructed small molecules to facilitate highly efficient screening experiments. These …

DNA-encoded libraries (DELs) provide the means to make and screen millions of diverse
compounds against a target of interest in a single experiment. However, despite producing …

DNA-encoded library (DEL) is a powerful ligand discovery technology that has been widely
adopted in the pharmaceutical industry. DEL selections are typically performed with a …

Bisphenol S (BPS), one of the most common alternatives for bisphenol A (BPA), has been
implied to increase the risk of breast cancer. Triple-negative breast cancer (TNBC) is a …

The concept of DNA-encoded libraries (DELs) enables the experimental screening of
billions of compounds simultaneously, offering an unprecedented boost in the coverage of …

DNA-encoded library (DEL) technology, especially when combined with machine learning
(ML), is a powerful method to discover novel inhibitors. DEL-ML can expand a larger …

DNA-Encoded Library (DEL) technology allows the screening of millions, or even billions, of
encoded compounds in a pooled fashion which is faster and cheaper than traditional …