The aim of this article is to describe the current and potential clinical translation of
pharmacological inhibitors of poly (ADP-ribose) polymerase (PARP) for the therapy of …

The pathophysiology of erectile dysfunction after radical prostatectomy (RP) is believed to
include neuropraxia, which leads to temporarily reduced oxygenation and subsequent …

Poly (ADP-ribosylation) consists in the conversion of β-NAD+ into ADP-ribose, which is then
bound to acceptor proteins and further used to form polymers of variable length and …

Purpose: Radical prostatectomy for prostate cancer frequently results in erectile dysfunction
and decreased quality of life. We investigated the effects of transplanting nonhematopoietic …

Introduction Erectile dysfunction (ED) following radical prostatectomy (RP) is a result of
inadvertent damage to the cavernous nerves that run close to the prostate capsula. The …

Porcine small intestinal submucosa (SIS) has been widely used in tunica albuginea (TA)
reconstructive surgery. Adipose tissue-derived stem cells (ADSCs) can repair damaged …

Data generated from a number of clinical investigations document that pharmacologic
rehabilitation programs provide a higher rate of recovery of erectile function following radical …

Despite nerve-sparing techniques, erectile dysfunction remains commonly observed after
radical prostatectomy due to neuropraxia to the cavernous nerves during surgery …

Introduction It is common for men to develop erectile dysfunction after radical prostatectomy.
The anatomy of the rat allows the cavernous nerve (CN) to be identified, dissected, and …

Penile (cavernous) nerves are readily damaged during radical prostatectomy, invariably
causing impotence. Erectile function can return, however this may take months or years and …