Nitric oxide (NO) plays important roles in physiology and pathology. This small molecule
regu-lates smooth muscle tone, functions as a neuro-transmitter, regulates cellular …

The region of conserved synteny on mouse chromosome 11/human 17q11–q21 is known to
carry a susceptibility gene (s) for intramacrophage pathogens. The region is rich in …

Tuberculosis (TB) is still one of the most difficult infectious diseases to treat, and the second
most frequent cause of death due to infectious disease throughout the world. The number of …

The development of a statistical model based on simple immunological markers which could
predict the response to tuberculosis treatment would facilitate clinical trials of new anti …

ABSTRACT A key function of monocytes/macrophages (Mφ) is to present antigens to T cells.
However, upon interaction with bacteria, Mφ lose their ability to effectively present soluble …

Studies have shown that tetracycline class antibiotics exhibit an ameliorating action with its
antioxidant property on increased oxidative stress in tissues, including heart. Since …

Activation of human macrophages infected with Mycobacterium tuberculosis was
investigated following exposure to microparticles (MP) possessing high anti-tubercular …

It has not been fully elucidated which of the components of the immune response against
Mycobacterium tuberculosis is indicative of resistance or susceptibility. The aim of this study …

An account is given of the immunological investigations carried out in Rosario (Argentina) to
identify suitable methods for the assessment of the efficacy of immunotherapy for TB. Some …

The European badger is recognised as a wildlife reservoir for bovine tuberculosis (bTB); the
control of which is complex, costly and controversial. Despite the importance of badgers in …