Increase in invasive fungal infections over the past few years especially in
immunocompromised patients prompted the search for new antifungal agents with improved …

A pharmacophore system has been found as 1, 2, 3‐triazole, a five‐membered heterocycle
ring with nitrogen heteroatoms. These heterocyclic compounds can be produced using …

Today's research is focused on developing new safe drugs of clinical importance. Nitrogen-
containing heterocycles are abundant in the common of therapeutic scaffolds. Triazoles are …

Three out of 16 newly synthesized 1, 3-dimethylxanthine derivatives (proxyphylline
analogues) exhibited consistencies between antifungal and anticancer properties …

1, 2, 3-Triazole, a five-membered heterocyclic nucleus, is widely recognized as a key
chromophore of great value in medicinal chemistry for delivering compounds possessing …

A series of 3, 4-dichloroisothiazole based novel strobilurin analogs were designed and
synthesized, and their structures were elucidated by NMR and HRMS, and the typical crystal …

A novel series of 5-(4-(benzyloxy) substituted phenyl)-3-((phenyl amino) methyl)-1, 3, 4-
oxadiazole-2 (3 H)-thione Mannich bases 6a–o were synthesized in good yield from the key …

Benjaminiella poitrasii, a dimorphic zygomycetous fungus contains more chitosan in the
mycelial cell wall than the cell wall of its yeast form. The optimized medium containing yeast …

Novel 1, 2, 3-triazole-linked β-lactam–fluconazole conjugates 12 (a–l) were designed and
synthesized. The compounds showed potent antifungal activity against two pathogenic …

ABSTRACT A dimorphic fungus Benjaminiella poitrasii contains high chitin/chitosan (35% of
the cell wall) in the mycelial (M) form than its yeast (Y) form (20% of the cell wall). However …