Engineering biomaterials with integrin‐binding activity is a very powerful approach to
promote cell adhesion, modulate cell behavior, and induce specific biological responses at …

Integrins are cell adhesion receptors predominantly important during normal and tumor
angiogenesis. A sequence present on several extracellular matrix proteins composed of Arg …

Immunotherapy is a promising strategy for targeting tumors. One emerging approach is to
harness the immune effector functions of natural antibodies to destroy tumor cells …

The interplay between chemical and mechanical signals plays an important role in cell
biology, and integrin receptors are the primary molecules involved in sensing and …

The fate decisions of human pluripotent stem (hPS) cells are governed by soluble and
insoluble signals from the microenvironment. Many hPS cell differentiation protocols use …

Cells respond to their environment in complex and sometimes poorly understood ways.
Protein, peptide and synthetic peptidomimetic ligands may all be used to stimulate cells via …

An integrin αVβ3-targeting linear RGD mimetic containing a small-molecule drug conjugate
(SMDC) was synthesized by combining the antimitotic agent monomethyl auristatin E …

Tropoelastin is the dominant monomer that assembles to form elastin, which confers
elasticity to vertebrate elastic tissues including skin, arteries, and lungs. Tropoelastin …

Synthetic human pluripotent stem cell (hPSC) culture surfaces with defined physical and
chemical properties will facilitate improved research and therapeutic applications of hPSCs …

Integrins are cell surface receptors for proteins of the extracellular matrix and plasma‐borne
adhesive proteins. Their involvement in diverse pathologies prompted medicinal chemists to …