Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …

In view of the importance of cancer stem cells (CSCs) in chemoresistance, metastasis and
recurrence, the biology of CSCs were explored in detail. Based on that, several modalities …

Long non‐coding RNAs are known as key regulators in the progression and metastasis of
breast cancer. MIAT originally has been considered as an lncRNA to be associated with a …

Mitotic slippage (MS), the incomplete mitosis that results in a doubled genome in interphase,
is a typical response of TP53-mutant tumors resistant to genotoxic therapy. These …

The ability of butyrate to promote differentiation of cancer cells has important implication for
colorectal cancer (CRC) prevention and therapy. In this study, we examined the effect of …

A subpopulation within cancer, known as cancer stem cells (CSCs), regulates tumor
initiation, chemoresistance, and metastasis. At a closer look, CSCs show functional …

Abstract Oct3/4, a transcription factor specifically expressed in mammalian totipotent
embryonic stem and germ cells, has a critical role in the regulation and maintenance of …

The epigenetic mechanisms underlying chemoresistance in cancer cells resulting from drug-
induced reversible senescence are poorly understood. Chemoresistant ESC-like embryonal …

The conversion of healthy stem cells into cancer stem cells (CSCs) is believed to underlie
tumor relapse after surgical removal and fuel tumor growth and invasiveness. CSCs often …

Materials and methods The CD133+ EpCAM+ cells were sorted from the HepG2 cell line
using magnetic cell sorting and specified by flow cytometry analysis of surface markers …