The vasa vasorum are a vital microvascular network supporting the outer wall of larger blood
vessels. Although these dynamic microvessels have been studied for centuries, the …

The vascular adventitia acts as a biological processing center for the retrieval, integration,
storage, and release of key regulators of vessel wall function. It is the most complex …

Mesenchymal stem/stromal cells (MSC) are currently the best candidate therapeutic cells for
regenerative medicine related to osteoarticular, muscular, vascular and inflammatory …

Rationale: Pericytes are key regulators of vascular maturation, but their value for cardiac
repair remains unknown. Objective: We investigated the therapeutic activity and mechanistic …

Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit
certain characteristics of osteocytes and chondrocytes led to the proposal that they could be …

Conventional views of the tunica adventitia as a poorly organized layer of vessel wall
composed of fibroblasts, connective tissue, and perivascular nerves are undergoing …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …

Background—Clinical trials in ischemic patients showed the safety and benefit of autologous
bone marrow progenitor cell transplantation. Non–bone marrow progenitor cells with …

We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells
(CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ …

We characterize a sonic hedgehog (Shh) signaling domain restricted to the adventitial layer
of artery wall that supports resident Sca1-positive vascular progenitor cells (AdvSca1). Using …