Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus

B Raman, DA Bluemke, TF Lüscher… - European heart …, 2022 - academic.oup.com
Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease
2019 (COVID-19), a condition characterized by the persistence of COVID-19 symptoms …

Post-COVID syndrome. A case series and comprehensive review

JM Anaya, M Rojas, ML Salinas, Y Rodríguez… - Autoimmunity …, 2021 - Elsevier
The existence of a variety of symptoms with a duration beyond the acute phase of COVID-
19, is referred to as post-COVID syndrome (PCS). We aimed to report a series of patients …

Symptom persistence despite improvement in cardiopulmonary health–insights from longitudinal CMR, CPET and lung function testing post-COVID-19

MP Cassar, EM Tunnicliffe, N Petousi… - …, 2021 - thelancet.com
Background The longitudinal trajectories of cardiopulmonary abnormalities and symptoms
following infection with coronavirus disease (COVID-19) are unclear. We sought to describe …

Long COVID: major findings, mechanisms and recommendations

HE Davis, L McCorkell, JM Vogel… - Nature Reviews …, 2023 - nature.com
Long COVID is an often debilitating illness that occurs in at least 10% of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms …

Remodeling of T cell dynamics during long COVID is dependent on severity of SARS-CoV-2 infection

M Wiech, P Chroscicki, J Swatler, D Stepnik… - Frontiers in …, 2022 - frontiersin.org
Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …

SARS-CoV-2 reinfections and long COVID in the post-omicron phase of the pandemic

F Boufidou, S Medić, V Lampropoulou… - International Journal of …, 2023 - mdpi.com
We are reviewing the current state of knowledge on the virological and immunological
correlates of long COVID, focusing on recent evidence for the possible association between …

A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae

PM George, A Reed, SR Desai, A Devaraj… - Science translational …, 2022 - science.org
Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment

Z Thomson, Z He, E Swanson, K Henderson… - Nature …, 2023 - nature.com
Age-associated changes in the T cell compartment are well described. However, limitations
of current single-modal or bimodal single-cell assays, including flow cytometry, RNA-seq …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

A Santa Cruz, A Mendes-Frias… - Nature …, 2023 - nature.com
Several millions of individuals are estimated to develop post-acute sequelae SARS-CoV-2
condition (PASC) that persists for months after infection. Here we evaluate the immune …