Intervertebral disc degeneration—Current therapeutic options and challenges

A Samanta, T Lufkin, P Kraus - Frontiers in Public Health, 2023 - frontiersin.org
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …

The magic staff: a comprehensive overview of baculovirus-based technologies applied to human and animal health

ML Pidre, PN Arrías, LC Amorós Morales… - Viruses, 2022 - mdpi.com
Baculoviruses are enveloped, insect-specific viruses with large double-stranded DNA
genomes. Among all the baculovirus species, Autographa californica multiple …

Strategies for enhancing immunity against avian influenza virus in chickens: A review

N Alqazlan, J Astill, S Raj, S Sharif - Avian Pathology, 2022 - Taylor & Francis
Poultry infection with avian influenza viruses (AIV) is a continuous source of concern for
poultry production and human health. Uncontrolled infection and transmission of AIV in …

The downstream bioprocess toolbox for therapeutic viral vectors

R Kilgore, A Minzoni, S Shastry, W Smith… - … of Chromatography A, 2023 - Elsevier
Viral vectors are poised to acquire a prominent position in modern medicine and
biotechnology owing to their role as delivery agents for gene therapies, oncolytic agents …

Nanotechnology in development of next generation of stent and related medical devices: Current and future aspects

P Islam, S Schaly, AK Abosalha… - Wiley …, 2024 - Wiley Online Library
Coronary stents have saved millions of lives in the last three decades by treating
atherosclerosis especially, by preventing plaque protrusion and subsequent aneurysms …

Viral vector vaccines against ASF: Problems and prospectives

RK Ravilov, AA Rizvanov, DN Mingaleev… - Frontiers in Veterinary …, 2022 - frontiersin.org
African swine fever (ASF) is a highly contagious viral disease affecting pigs, with mortality
rates a primary focus as they can reach up to 100%. The widespread and colossal economic …

Controlled and customizable baculovirus NOS3 gene delivery using PVA-based hydrogel systems

S Schaly, P Islam, JL Boyajian, R Thareja, A Abosalha… - Plos one, 2023 - journals.plos.org
Nitric oxide synthase 3 (NOS3) eluting polyvinyl alcohol-based hydrogels have a large
potential in medical applications and device coatings. NOS3 promotes nitric oxide and …

Baculovirus Expressing Tumor Growth Factor-β1 (TGFβ1) Nanoshuttle Augments Therapeutic Effects for Vascular Wound Healing: Design and In Vitro Analysis

P Islam, A Abosalha, S Schaly… - ACS Pharmacology & …, 2024 - ACS Publications
One of the major challenges in vascular tissue regeneration is effective wound healing that
can be resolved by an innovative targeted nanoshuttle that delivers growth factors to blood …

Genome Analysis of an Alphabaculovirus Isolated from the Larch Looper, Erannis ankeraria

L Liu, Z Zhang, C Liu, L Qu, D Wang - Viruses, 2021 - mdpi.com
The larch looper, Erannis ankeraria Staudinger (Lepidoptera: Geometridae), is one of the
major insect pests of larch forests, widely distributed from southeastern Europe to East Asia …

The Use of Baculovirus-Mediated Gene Expression in Mammalian Cells for Recombinant Protein Production

J Flock, Y Xie, R Lemaitre, K Lapouge… - … Protein Expression in …, 2024 - Springer
Baculovirus-mediated gene expression in mammalian cells, BacMam, is a useful alternative
to transient transfection for recombinant protein production in various types of mammalian …