Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since
become a well-studied therapy for cancer and various non-malignant diseases including …

Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Photodynamic therapy (PDT) is already being used in the treatment of many cancers. This
review examines its components and the new developments in our understanding of its …

Photodynamic therapy (PDT) is a light-based intervention with a long and successful clinical
track record for both oncology and non-malignancies. In cancer patients, a photosensitizing …

Photochemical internalisation (PCI) is a unique intervention which involves the release of
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …

Aggregation‐induced emission (AIE) molecules possess notable advantages outperforming
traditional aggregation caused quenching (ACQ) materials on various aspects. They are …

Psoriasis is a chronic inflammatory skin disease that presents increased expression of tumor
necrosis factor α (TNFα), a proinflammatory cytokine. The discovery of RNA interference …

The term ribosome-inactivating protein (RIP) is used to denominate proteins mostly of plant
origin, which have N-glycosidase enzymatic activity leading to a complete destruction of the …

Protein-based targeted toxins play an increasingly important role in targeted tumor
therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major …

The cancer stem cell (CSC) marker CD133 is an attractive target to improve antitumor
therapy. We have used photochemical internalization (PCI) for the endosomal escape of the …