Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors

AP Klein - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has
more than doubled over the past 25 years. The highest incidence regions for pancreatic …

Pancreatic cancer

JD Mizrahi, R Surana, JW Valle, RT Shroff - The Lancet, 2020 - thelancet.com
Pancreatic cancer is a highly fatal disease with a 5-year survival rate of approximately 10%
in the USA, and it is becoming an increasingly common cause of cancer mortality. Risk …

Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis

J Cai, H Chen, M Lu, Y Zhang, B Lu, L You, T Zhang… - Cancer letters, 2021 - Elsevier
Pancreatic cancer is a malignancy with poor prognosis and high mortality. The recent
increase in pancreatic cancer incidence and mortality has resulted in an increased number …

Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review

J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

NCCN guidelines insights: genetic/familial high-risk assessment: breast, ovarian, and pancreatic, version 1.2020: featured updates to the NCCN guidelines

MB Daly, R Pilarski, MB Yurgelun, MP Berry… - Journal of the National …, 2020 - jnccn.org
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic provide recommendations for genetic testing and counseling for hereditary …

[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges

AD Singhi, EJ Koay, ST Chari, A Maitra - Gastroenterology, 2019 - Elsevier
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) …

M Goggins, KA Overbeek, R Brand, S Syngal… - Gut, 2020 - gut.bmj.com
Background and aim The International Cancer of the Pancreas Screening Consortium met in
2018 to update its consensus recommendations for the management of individuals with …

Association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer

C Hu, SN Hart, EC Polley, R Gnanaolivu, H Shimelis… - Jama, 2018 - jamanetwork.com
Importance Individuals genetically predisposed to pancreatic cancer may benefit from early
detection. Genes that predispose to pancreatic cancer and the risks of pancreatic cancer …

Pancreatic adenocarcinoma

DP Ryan, TS Hong, N Bardeesy - New England journal of …, 2014 - Mass Medical Soc
Pancreatic Adenocarcinoma | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Risk of neoplastic progression in individuals at high risk for pancreatic cancer undergoing long-term surveillance

MI Canto, JA Almario, RD Schulick, CJ Yeo, A Klein… - Gastroenterology, 2018 - Elsevier
Background & Aims Screening of individuals who have a high risk of pancreatic ductal
adenocarcinoma (PDAC), because of genetic factors, frequently leads to identification of …