Currently, nearly two billion people are at risk of contracting malaria and the incidence of this
disease is dramatically increasing because many Plasmodium falciparum strains, the …

Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild
to severe malaria infection. Given the therapeutic significance of AS and the necessity of …

Increasing costs, much time consumption and high risk of failure associated with the process
of de novo development of new anticancer drugs have prompted the pharmaceutical …

Background Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone,
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …

Cancer has become a global health problem, accounting for one out of six deaths. Despite
the recent advances in cancer therapy, there is still an ever-growing need for readily …

Abstract Background. Dihydroartemisinin-piperaquine (DP) is a new and relatively
inexpensive artemisinin-containing fixed-combination antimalarial treatment. An adult …

Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene
lactone structure. Because of its unique structural characteristics and promising anticancer …

Artesunate drug substance, for which a rectal capsule formulation is under development for
the treatment of severe malaria, when heated at 100° C for 39 h gives β‐artesunate …

Human cytomegalovirus (HCMV) is a major cause of disease in immunocompromised
individuals and the most common cause of congenital infection and neurosensorial disease …

Background Artesunate (ART) is an artemisinin derivative used as monotherapy for the
treatment of severe malaria and in combination with a partner drug for non-severe malaria …