The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Simple Summary Oxidative stress occurs within biological systems when free radicals,
classified as reactive oxygen species and reactive nitrogen species, are in excess. The …

For a number of years, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet
clinical exploitation of these hypotheses by pharmacological modulation of ROS has been …

The heterogeneity of biological processes driving the severity of nonalcoholic fatty liver
disease (NAFLD) as reflected in the transcriptome and the relationship between the …

Abstract The NADPH Oxidases (NOX) catalyze the deliberate production of reactive oxygen
species (ROS) and are established regulators of redox-dependent processes across diverse …

The lung is a delicate organ with a large surface area that is continuously exposed to the
external environment, and is therefore highly vulnerable to exogenous sources of oxidative …

New Findings What is the topic of this review? This review provides a comprehensive
overview of Nox5 from basic biology to human disease and highlights unique features of this …

Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …