In this review, we summarize the origin and advancements of iridium-catalyzed asymmetric
allylic substitution reactions during the past two decades. Since the first report in 1997, Ir …

Efficient and reliable amplification of chirality has borne its greatest fruit with transition metal-
catalyzed reactions since enantiocontrol may often be imposed by replacing an achiral or …

Development of asymmetric metal-catalyzed reactions has played a significant role in
allowing synthetic access to biologically important molecules. While the most widely utilized …

Practical asymmetric catalysis using transition metal complexes was inspired by the work of
Kagan1 and Knowles. 2 Their important results, based on the use of chiral phosphines as …

The diversity of mechanisms for enantiodiscrimination and of bond types that can be formed
make Pd-catalyzed asymmetric allylic alkylation a powerful key step for simplification of …

Discovering efficient methods for gaining access to enantiomerically pure compounds in the
development of pharmaceuticals, agrochemicals, and flavors has been a great challenge for …

A new catalytic asymmetric process, the iridium-catalyzed enantioselective allylic amination
of (E)-cinnamyl and terminal aliphatic allylic carbonates, was developed by exploring …

Cationic iridium (I) complexes of chiral phosphanodihydrooxazoles were used as catalysts
for the enantioselective hydrogenation of prochiral N‐alkyl and N‐aryl imines. The …

Studies were conducted to determine possible intermediates in the highly enantioselective,
iridium-catalyzed amination and etherification of allylic carbonates, and these studies …

Ir-Catalysed allylic substitution is supplementing the traditional Pd-catalysed variant. With
simple, easily available monosubstituted allylic acetates and carbonates as substrates, Ir …