Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …

Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic
single-base damage that appear to have minimal effects on the helix. Since its discovery in …

Background: SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage
in the lungs in the setting of an overzealous immune response whose origin remains …

Abstract SARS-CoV-2 infection-induced aggravation of host innate immune response not
only causes tissue damage and multiorgan failure in COVID-19 patients but also induces …

Simple Summary Defective DNA damage response (DDR) is a hallmark of cancer leading to
genomic instability. Up to 15–20% of colorectal cancers carry alterations in DDR. However …

Fusobacterium nucleatum (Fn) has been extensively studied for its connection to colorectal
cancer (CRC) and its potential role in chemotherapy resistance. Studies indicate that Fn is …

Background Engulfment and cell motility protein 1 (ELMO1) is a key protein for innate
immunity since it is required for the clearance of apoptotic cells and pathogenic bacteria as …

Although genetics affects early childhood caries (ECC) risk, few studies have focused on
finding its specific genetic determinants. Here, we performed genome-wide association …

The anaerobic bacterium Fusobacterium nucleatum is significantly associated with human
colorectal cancer (CRC) and is considered a significant contributor to the disease. The …

Colorectal cancer (CRC) is the second most common malignancy causing cancer‑related
mortality globally. It is the third most common type of cancer detected worldwide. The recent …