This review critically summarizes the neuropathology and genetics of schizophrenia, the
relationship between them, and speculates on their functional convergence. The …

The historical and genetic foundations of our current understanding of schizophrenia are
reviewed, as are the present and future directions for research. Genetic epidemiological …

The cause of schizophrenia is unknown, but it has a significant genetic component.
Pharmacologic studies, studies of gene expression in man, and studies of mouse mutants …

Background Velo-cardio-facial syndrome (VCFS), a syndrome characterized by an
increased frequency of schizophrenia and bipolar disorder, is associated with small …

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …

The central theme of personalized medicine is the premise that an individual's unique
physiologic characteristics play a significant role in both disease vulnerability and in …

Attention-deficit/hyperactivity disorder, ADHD, is a common and highly heritable
neuropsychiatric disorder that is seen in children and adults. Although heritability is …

Badner and Gershon (2001) presented a technique of meta-analysis of linkage data that
could be applied to published genome scans. It combines the reported P-values of …

A map of 191 single-nucleotide polymorphism (SNPs) was built across a 5-Mb segment from
chromosome 13q34 that has been genetically linked to schizophrenia. DNA from 213 …

Schizophrenia is a debilitating mental illness that affects 1% of the population. Despite
intensive study, its molecular etiology remains enigmatic. Like many common diseases …