Lifespan and healthspan: past, present, and promise

EM Crimmins - The Gerontologist, 2015 - academic.oup.com
The past century was a period of increasing life expectancy throughout the age range. This
resulted in more people living to old age and to spending more years at the older ages. It is …

The effect of fall prevention exercise programmes on fall induced injuries in community dwelling older adults: systematic review and meta-analysis of randomised …

F El-Khoury, B Cassou, MA Charles, P Dargent-Molina - BMj, 2013 - bmj.com
Objective To determine whether, and to what extent, fall prevention exercise interventions for
older community dwelling people are effective in preventing different types of fall related …

Disability incidence and functional decline among older adults with major chronic diseases

JH Fong - BMC geriatrics, 2019 - Springer
Background More than 80% of elderly Americans have at least one chronic disease. While
past studies have shown that hierarchical patterns of functional loss may differ by gender …

Ageing populations: the challenges ahead

K Christensen, G Doblhammer, R Rau, JW Vaupel - The lancet, 2009 - thelancet.com
If the pace of increase in life expectancy in developed countries over the past two centuries
continues through the 21st century, most babies born since 2000 in France, Germany, Italy …

Biodemography of human ageing

JW Vaupel - Nature, 2010 - nature.com
Human senescence has been delayed by a decade. This finding, documented in 1994 and
bolstered since, is a fundamental discovery about the biology of human ageing, and one …

Mortality and morbidity trends: is there compression of morbidity?

EM Crimmins, H Beltrán-Sánchez - Journals of Gerontology …, 2011 - academic.oup.com
Objective. This paper reviews trends in mortality and morbidity to evaluate whether there has
been a compression of morbidity. Methods. Review of recent research and analysis of recent …

Disability and care needs among older Americans

VA Freedman, BC Spillman - The Milbank Quarterly, 2014 - Wiley Online Library
Policy Points: Nearly half of elderly Medicare beneficiaries have difficulty performing daily
activities without assistance or receive help with such activities. This help is most often from …

[HTML][HTML] Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions

A Mobasheri, G Kalamegam, G Musumeci, ME Batt - Maturitas, 2014 - Elsevier
Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …

Substantial health and economic returns from delayed aging may warrant a new focus for medical research

DP Goldman, D Cutler, JW Rowe, PC Michaud… - Health …, 2013 - healthaffairs.org
Recent scientific advances suggest that slowing the aging process (senescence) is now a
realistic goal. Yet most medical research remains focused on combating individual diseases …

Aging, disability and frailty

E Topinková - Annals of Nutrition and Metabolism, 2008 - karger.com
Despite multiple and often overlapping definitions of disability and frailty, both are common
clinical characteristics of aged individuals though not identical. The geriatric syndrome of …