Modulation of autophagy, apoptosis and oxidative stress: A clue for repurposing metformin in photoaging

DK Mostafa, OA Nayel, S Abdulmalek… - …, 2022 - Springer
Long-term sun exposure is the commonest cause of photoaging, where mutual interplay
between autophagy, oxidative stress, and apoptosis is incriminated. In combating …

Monoolein-based nanodispersions for cutaneous co-delivery of methylene blue and metformin: Thermal and structural characterization and effects on the cutaneous …

LGF Donadon, GC Salata, TP Gonçalves… - International Journal of …, 2023 - Elsevier
This study evaluated the potential of monoolein (MO)-based nanodispersions to promote the
cutaneous co-delivery of metformin (MET) and methylene blue (MB) for the treatment of non …

Compatibility of Different Formulations in Pentravan® and Pentravan® Plus for Transdermal Drug Delivery

H Polonini, S Taylor, C Zander - Scientia Pharmaceutica, 2021 - mdpi.com
The potential therapeutic benefit of transdermal delivery systems for some active
pharmaceutical ingredients (APIs) has been well-established for decades within the …

Developing an analytical method by HPLC for simultaneous quantification of methylene blue and metformin applied to in vitro skin permeation and retention studies

L de Carvalho Matos, LA Calixto… - Biomedical …, 2021 - Wiley Online Library
The aim of this study was to develop an HPLC method for simultaneous quantification of
metformin (MET) and methylene blue (MB) in in vitro skin permeation/retention studies, in …

Quantifying skin permeation of a novel metformin lotion using modified hydrophilic interaction liquid chromatography

DJ Maloney, J Zhang, S Bhargava, MCV Hogan… - Bioanalysis, 2024 - Taylor & Francis
Aim: This study aimed to quantify the permeation of metformin (Met) lotion through pig ear
skin using high-performance liquid chromatography, specifically hydrophilic interaction …

Development of a transdermal gel containing modified metformin: a more effective approach to the treatment of type II Diabetes Mellitus (T2DM)

JC da Silva, LFF Pinto, ÉM da Silva… - Caderno …, 2024 - ojs.studiespublicacoes.com.br
Pharmacotherapy for type II diabetes mellitus (T2DM) aims to reduce blood glucose levels,
with metformin, a widely administered oral hypoglycemic agent. However, its oral efficacy …

[PDF][PDF] Pentravan®

OVT do Mercado Magistral - institucional.farmacam.com.br
O Pentravan® é um veículo transdérmico com estudos de permeação ex vivo através de
câmaras de difusão que garantem uma similaridade com corpo humano. A escolha por …

[PDF][PDF] Směsi pomocných látek pro individuální přípravu a možnosti jejich použití v současné lékárenské praxi

E Procházková - solen.cz
Individuální příprava byla, je a zajisté i bude důležitou součástí služeb poskytovaných
lékárnou. V moderní praxi mají lékárny k dispozici celou řadu směsí pomocných látek …