Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis
Cancer divergence has many facets other than being considered a genetic term. It is a
tremendous challenge to understand the metastasis and therapy response in cancer …
tremendous challenge to understand the metastasis and therapy response in cancer …
Crosstalk of inflammatory cytokines within the breast tumor microenvironment
O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …
The dual role of tumor necrosis factor-alpha (TNF-α) in breast cancer: molecular insights and therapeutic approaches
D Cruceriu, O Baldasici, O Balacescu… - Cellular Oncology, 2020 - Springer
Background Breast cancer is the most prevalent cancer among women worldwide and the
fifth cause of death among all cancer patients. Breast cancer development is driven by …
fifth cause of death among all cancer patients. Breast cancer development is driven by …
Hypoxia-induced epithelial-mesenchymal transition in cancers: HIF-1α and beyond
Metastasis is the main cause of cancer-related mortality. Although the actual process of
metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been …
metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been …
Partial EMT in head and neck cancer biology: a spectrum instead of a switch
Our understanding of epithelial-to-mesenchymal transition (EMT) has slowly evolved from a
simple two state, binary model to a multi-step, dynamic continuum of epithelial-to …
simple two state, binary model to a multi-step, dynamic continuum of epithelial-to …
NF-kappaB is involved in the regulation of EMT genes in breast cancer cells
BRB Pires, AL Mencalha, GM Ferreira, WF De Souza… - PloS one, 2017 - journals.plos.org
The metastatic process in breast cancer is related to the expression of the epithelial-to-
mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG, SIP1 and TWIST1 …
mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG, SIP1 and TWIST1 …
Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
The role of tumor necrosis factor in manipulating the immunological response of tumor microenvironment
The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …
review, we aim to provide an updated insight into the TME with a focus on the effects of …
Tumor necrosis factor α blockade: an opportunity to tackle breast cancer
MF Mercogliano, S Bruni, PV Elizalde… - Frontiers in …, 2020 - frontiersin.org
Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality
by malignancy in women and represents a main problem for public health worldwide. Tumor …
by malignancy in women and represents a main problem for public health worldwide. Tumor …
Cancer cell plasticity: Impact on tumor progression and therapy response
V da Silva-Diz, L Lorenzo-Sanz… - Seminars in cancer …, 2018 - Elsevier
Most tumors exhibit intra-tumor heterogeneity, which is associated with disease progression
and an impaired response to therapy. Cancer cell plasticity has been proposed as being an …
and an impaired response to therapy. Cancer cell plasticity has been proposed as being an …