Polyunsaturated fatty acids: what is their role in treatment of psychiatric disorders?

P Bozzatello, P Rocca, E Mantelli, S Bellino - International Journal of …, 2019 - mdpi.com
In the central nervous system omega-3 fatty acids modulate cell signaling and affect
dopaminergic and serotonergic pathways. On this basis, a new application for omega-3 fatty …

Drug reprofiling history and potential therapies against Parkinson's disease

K Latif, A Ullah, AD Shkodina, DI Boiko… - Frontiers in …, 2022 - frontiersin.org
Given the high whittling down rates, high costs, and moderate pace of new medication,
revelation, and improvement, repurposing “old” drugs to treat typical and uncommon …

Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity …

SM Ahmadi-Soleimani, GY Amiry, E Khordad… - Life Sciences, 2023 - Elsevier
In the present study, the main objective was to reveal whether treatment by Omega-3 fatty
acids could prevent the adverse effects of adolescent nicotine withdrawal on spatial and …

Improvement of carotenoid bioaccessibility from spinach by co-ingesting with excipient nanoemulsions: impact of the oil phase composition

K Yao, DJ McClements, J Xiang, Z Zhang, Y Cao… - Food & function, 2019 - pubs.rsc.org
Many of the carotenoids found naturally in fruits and vegetables are beneficial to human
health, but they often have low oral bioavailability because of their high hydrophobicity. In …

Apoptosis and astrogliosis perturbations and expression of regulatory inflammatory factors and neurotransmitters in acrylamide-induced neurotoxicity under ω3 fatty …

SS Elblehi, OI El Euony, YS El-Sayed - Neurotoxicology, 2020 - Elsevier
This study was aimed to investigate the potential ameliorative effects of omega-3 (ω3) fatty
acids against acrylamide (ACR)-induced neurotoxicity. Thirty-two adult male Sprague …

Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder

B Sur, B Lee - Journal of Natural Medicines, 2022 - Springer
Post-traumatic stress disorder (PTSD) is a serious mental disorder that can develop after
exposure to extreme stress. Korean red ginseng, whose major active component is …

Cerebrolysin prevents sleep deprivation induced memory impairment and oxidative stress

KH Alzoubi, FF Al-Jamal, AF Mahasneh - Physiology & behavior, 2020 - Elsevier
Sleep plays a critical role in body health maintenance and well-being throughout a lifetime.
Sleeplessness is the most prevalent feature in the modernist societies, which impairs …

[HTML][HTML] DHA-rich fish oil and Tualang honey reduce chronic stress-induced oxidative damage in the brain of rat model

MA Asari, KNS Sirajudeen, NAM Yusof… - Journal of Traditional and …, 2022 - Elsevier
Background Exposure to chronic stress induces oxidative damage which alters the dynamic
balance between antioxidant and pro-oxidant activities in the brain. Tualang honey (TH) is a …

Myricetin Inhibited Fear and Anxiety‐Like Behaviors by HPA Axis Regulation and Activation of the BDNF‐ERK Signaling Pathway in Posttraumatic Stress Disorder …

B Sur, B Lee - Evidence‐Based Complementary and …, 2022 - Wiley Online Library
Posttraumatic stress disorder (PTSD) is a stress‐related psychiatric or mental disorder
characterized by experiencing a traumatic stress. The cause of such PTSD is dysregulation …

Development of chitosan lipid nanoparticles to alleviate the pharmacological activity of piperine in the management of cognitive deficit in diabetic rats

AB Darwish, AM Mohsen, S ElShebiney, R Elgohary… - Scientific Reports, 2024 - nature.com
The aim of the present study was to prepare and evaluate Piperine (PP) loaded chitosan
lipid nanoparticles (PP-CLNPs) to evaluate its biological activity alone or in combination with …