Background Several studies have suggested that diabetes mellitus (DM) increases the risk
of active tuberculosis (TB). The rising prevalence of DM in TB-endemic areas may adversely …

Objectives: Tuberculosis (TB) remains a major global public health problem. In the past, a
relationship between TB and diabetes mellitus (DM) was recognized, and its importance …

The historical impression that tuberculosis was an inherited disorder has come full circle and
substantial evidence now exists of the human genetic contribution to susceptibility to …

OBJECTIVE: To explore the potential role of vitamin D receptor (VDR) gene and natural-
resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms in …

Background Natural resistance associated macrophage protein 1 (NRAMP1), encoded by
the SLC11A1 gene, has been described to regulate macrophage activation and be …

A link between urban living and disease is seen in recent and historical records, but the
presence of this association in prehistory has been difficult to assess. If the transition to …

OBJECTIVE: Although many case-control studies have investigated the association between
the SLC11A1 gene polymorphisms and tuberculosis (TB) susceptibility, results were …

Several candidate gene studies have provided evidence for a role of host genetics in
susceptibility to tuberculosis (TB). However, the results of these studies have been very …

Objective and background: Polymorphisms in the natural resistance‐associated
macrophage protein gene 1 (NRAMP1) and tumour necrosis factor (TNF)‐α gene have been …

Mycobacterial disease remains a serious global health problem. Tuberculosis causes more
than 2 million deaths a year, and leprosy is still a cause of severe disability in many parts of …