Tall stature and eunuchoid body proportions characterize patients with 47, XXY Klinefelter
syndrome, whereas patients with 45, X Turner syndrome are characterized by impaired …

The testes are active during gestation, as well as during early infancy. Testosterone
elevation during fetal development has been shown to play a role in human …

Context: Estrogens and androgens play key roles for pubertal onset and sexual maturation.
Most currently used immunoassays are not sensitive enough to accurately measure the low …

A genetic origin is estimated in 30% of infertile men with the common phenotypes of oligo-or
azoospermia, but the pathogenesis of spermatogenic failure remains frequently obscure. To …

MK‐7246, an antagonist of the chemoattractant receptor on T helper type 2 (Th2) cells, is
being developed for the treatment of respiratory diseases. In a first‐in‐human study, we …

Background Naturally occurring germline gene deletions (KO) represent a unique setting to
interrogate gene functions. Complete deletions and differential expression of the human …

Background The metabolism and excretion of the anabolic steroid testosterone occurs by
glucuronidation to the conjugate testosterone glucuronide which is then excreted in urine …

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and thus
influence many cellular and physiological processes. miRNAs are also present in cell-free …

Ethnicity has been found to influence urinary testosterone glucuronide to epitestosterone
glucuronide (T/E) ratios among athletes. Uridine diphospho‐glucuronosyltransferase 2B17 …

Objective: The aim of this study was to determine the association of the Helicobacter pylori
virulence factors, cytotoxin-associated gene A (CagA) and vacuolating cytotoxin A (VacA) …