The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: a review focus on signaling pathways
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …
Unlocking novel therapeutic avenues in glioblastoma: Harnessing 4-amino cyanine and miRNA synergy for next-gen treatment convergence
K Sandhanam, T Tamilanban, K Manasa… - Neuroscience, 2024 - Elsevier
Glioblastoma (GBM) poses a formidable challenge in oncology due to its aggressive nature
and dismal prognosis, with average survival rates around 15 months despite conventional …
and dismal prognosis, with average survival rates around 15 months despite conventional …
Apilarnil exerts neuroprotective effects and alleviates motor dysfunction by rebalancing M1/M2 microglia polarization, regulating miR-155 and miR-124 expression in a …
Microglial activation contributes to the neuropathology of Parkinson's disease (PD).
Inhibiting M1 while simultaneously boosting M2 microglia activation may therefore be a …
Inhibiting M1 while simultaneously boosting M2 microglia activation may therefore be a …
The emerging role of miRNAs in myocardial infarction: From molecular signatures to therapeutic targets
Globally, myocardial infarction (MI) and other cardiovascular illnesses have long been
considered the top killers. Heart failure and mortality are the results of myocardial apoptosis …
considered the top killers. Heart failure and mortality are the results of myocardial apoptosis …
Parkinson's Disease Diagnosis Using Deep Learning: A Bibliometric Analysis and Literature Review
Parkinson's Disease (PD) is a progressive neurodegenerative illness triggered by
decreased dopamine secretion. Deep Learning (DL) has gained substantial attention in PD …
decreased dopamine secretion. Deep Learning (DL) has gained substantial attention in PD …
miRNAs as modulators of neuroinflammation and excitotoxicity: Implications for stroke therapeutics
MS Elballal, OA Mohammed, MB Zaki… - … -Research and Practice, 2024 - Elsevier
Stroke is a widespread neurological disorder associated with physical disabilities, mortality,
and economic burden. In recent decades, substantial progress has been achieved in …
and economic burden. In recent decades, substantial progress has been achieved in …
The potential role of miRNAs in the pathogenesis of schizophrenia-A focus on signaling pathways interplay
Abstract microRNAs (miRNAs) play a crucial role in brain growth and function. Hence,
research on miRNA has the potential to reveal much about the etiology of neuropsychiatric …
research on miRNA has the potential to reveal much about the etiology of neuropsychiatric …
Unveiling the regulatory role of miRNAs in stroke pathophysiology and diagnosis
Stroke, a major global cause of mortality, leads to a range of problems for those who survive.
Besides its brutal events, stroke also tends to have a characteristic of recurrence, making it a …
Besides its brutal events, stroke also tends to have a characteristic of recurrence, making it a …
miR-142-3p alleviates neuronal apoptosis in Parkinson's disease via negatively regulating C9orf72
Q Meng, J Chen, Y Liang, X Zhang, J Ding, Y Fang… - Neuroscience …, 2024 - Elsevier
Although microRNA (miRNA) have important clinical prospects in the early diagnosis and
treatment of PD, the functions and mechanisms of miRNAs in PD models remain poorly …
treatment of PD, the functions and mechanisms of miRNAs in PD models remain poorly …