Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Neuronal voltage-gated calcium channels: structure, function, and dysfunction

BA Simms, GW Zamponi - Neuron, 2014 - cell.com
Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

[HTML][HTML] Neuromodulation of hippocampal long-term synaptic plasticity

J Palacios-Filardo, JR Mellor - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Acetylcholine, noradrenaline, dopamine and serotonin all facilitate long-term
synaptic plasticity.•Neuromodulators facilitate long-term synaptic plasticity by common and …

Cholinergic modulation of hippocampal network function

LM Teles-Grilo Ruivo, JR Mellor - Frontiers in synaptic neuroscience, 2013 - frontiersin.org
Cholinergic septohippocampal projections from the medial septal area to the hippocampus
are proposed to have important roles in cognition by modulating properties of the …

[HTML][HTML] Schizophrenia genomics: convergence on synaptic development, adult synaptic plasticity, or both?

J Hall, NJ Bray - Biological Psychiatry, 2022 - Elsevier
Large-scale genomic studies of schizophrenia have identified hundreds of genetic loci
conferring risk to the disorder. This progress offers an important route toward defining the …

Presynaptic Cav3. 2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons

MO Jacus, VN Uebele, JJ Renger… - Journal of …, 2012 - Soc Neuroscience
It is generally accepted that presynaptic transmitter release is mainly regulated by subtypes
of neuronal high-voltage-activated Ca2+ channels. Here for the first time, we examined the …

Striatal cholinergic interneurons Drive GABA release from dopamine terminals

AB Nelson, N Hammack, CF Yang, NM Shah, RP Seal… - Neuron, 2014 - cell.com
Striatal cholinergic interneurons are implicated in motor control, associative plasticity, and
reward-dependent learning. Synchronous activation of cholinergic interneurons triggers …

Septal cholinergic input to CA2 hippocampal region controls social novelty discrimination via nicotinic receptor-mediated disinhibition

D Pimpinella, V Mastrorilli, C Giorgi, S Coemans… - elife, 2021 - elifesciences.org
Acetylcholine (ACh), released in the hippocampus from fibers originating in the medial
septum/diagonal band of Broca (MSDB) complex, is crucial for learning and memory. The …

A Cav3. 2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis

N Weiss, S Hameed, JM Fernández-Fernández… - Journal of Biological …, 2012 - ASBMB
T-type calcium channels represent a key pathway for Ca 2+ entry near the resting
membrane potential. Increasing evidence supports a unique role of these channels in fast …

Direct excitation of parvalbumin‐positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

F Yi, J Ball, KE Stoll, VC Satpute… - The Journal of …, 2014 - Wiley Online Library
Key points Parvalbumin‐containing (PV) neurons from mouse CA1 hippocampus (HC) and
prefrontal cortex exhibit a fast spiking phenotype in vitro. Within CA1, HC PV cells are mainly …