[HTML][HTML] Recent advances in asymmetric organocatalyzed conjugate additions to nitroalkenes

DA Alonso, A Baeza, R Chinchilla, C Gómez… - Molecules, 2017 - mdpi.com
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes
is a very interesting tool for the construction of highly functionalized synthetic building …

Recent Advances in Organocatalytic Asymmetric Michael Addition Reactions to α, β‐Unsaturated Nitroolefins

T Das, S Mohapatra, NP Mishra, S Nayak… - …, 2021 - Wiley Online Library
An organocatalyzed asymmetric Michael addition reaction has been established as the most
relevant and dynamic research area for the construction of chiral carbon‐carbon and carbon …

Syntheses and reactivity of spiro-epoxy/aziridine oxindole cores: developments in the past decade

AP Sakla, P Kansal, N Shankaraiah - Organic & Biomolecular …, 2020 - pubs.rsc.org
Spiro-epoxy/aziridine oxindole frameworks are considered as an efficient structural toolbox
to obtain C3-functionalised oxindole derivatives. These 3, 3′-spiro-cyclic precursors are …

Reliability of click chemistry on drug discovery: A personal account

N Shankaraiah, AP Sakla, K Laxmikeshav… - The Chemical …, 2020 - Wiley Online Library
The unprecedented efficiency, reliability and adaptability in drug discovery, with the growing
number of applications and impact, have made Click Chemistry fascinating to the scientific …

Organocatalytic asymmetric nitro-michael reactions

A Maria Faísca Phillips - Current Organic Synthesis, 2016 - ingentaconnect.com
The formation of CC and CX bonds is a fundamental process in synthesis. In recent years
organocatalysis has become a powerful tool to achieve these steps in a highly …

Pyrrolidine-based chiral porous polymers for heterogeneous organocatalysis in water

Y Lan, C Yang, Y Zhang, W An, H Xue, S Ding… - Polymer …, 2019 - pubs.rsc.org
The properties of high stability, inherent porosity, and tunable nature of porous organic
polymers (POPs) make these materials ideal catalytic nanoreactors, which can be …

Diaminomethylenemalononitrile as a Chiral Single Hydrogen Bond Catalyst: Application to Enantioselective Conjugate Addition of α‐Branched Aldehydes

M Kawada, R Tsuyusaki, K Nakashima… - Chemistry–An Asian …, 2021 - Wiley Online Library
An improved diaminomethylenemalononitrile organocatalyst, bearing a N, N‐disubstituted
structure, promoted enantioselective conjugate addition reaction of α‐branched aldehydes …

The catalytic, enantioselective Michael reaction

E Reyes, U Uria, JL Vicario, L Carrillo - Organic Reactions, 2004 - Wiley Online Library
The catalytic enantioselective Michael reaction is the conjugate addition of a resonance‐
stabilized carbanion to an electron‐poor olefin (an αβ‐unsaturated carbonyl compound or a …

[HTML][HTML] Asymmetric Michael addition organocatalyzed by α, β-dipeptides under solvent-free reaction conditions

CG Avila-Ortiz, L Díaz-Corona, E Jiménez-González… - Molecules, 2017 - mdpi.com
The application of six novel α, β-dipeptides as chiral organocatalysts in the asymmetric
Michael addition reaction between enolizable aldehydes and N-arylmaleimides or …

Stereoselective Aldol and Conjugate Addition Reactions Mediated by Proline‐Based Catalysts and Its Analogues: A Concise Review

DG Valapil, M Kadagathur… - European Journal of …, 2021 - Wiley Online Library
The application of amino acids and small peptides as asymmetric organocatalysts in the
aldol and conjugate addition reactions is a significant breakthrough in the past decade. The …