Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies

S Paul, E Candelario-Jalil - Experimental neurology, 2021 - Elsevier
Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Beyond the biomarker role: prostate-specific antigen (PSA) in the prostate cancer microenvironment

A Moradi, S Srinivasan, J Clements, J Batra - Cancer and Metastasis …, 2019 - Springer
The prostate-specific antigen (PSA) blood test is the accepted biomarker of tumor
recurrence. PSA levels in serum correlate with disease progression, though its diagnostic …

Characterization of human plasma-derived exosomal RNAs by deep sequencing

X Huang, T Yuan, M Tschannen, Z Sun, H Jacob, M Du… - BMC genomics, 2013 - Springer
Background Exosomes, endosome-derived membrane microvesicles, contain specific RNA
transcripts that are thought to be involved in cell-cell communication. These RNA transcripts …

[HTML][HTML] In vivo activation of a conserved microRNA program induces mammalian heart regeneration

A Aguirre, N Montserrat, S Zacchigna, E Nivet… - Cell stem cell, 2014 - cell.com
Heart failure is a leading cause of mortality and morbidity in the developed world, partly
because mammals lack the ability to regenerate heart tissue. Whether this is due to …

Androgen-responsive circular RNA circSMARCA5 is up-regulated and promotes cell proliferation in prostate cancer

Z Kong, X Wan, Y Zhang, P Zhang, Y Zhang… - Biochemical and …, 2017 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed cancers in males worldwide.
Circular RNA (circRNA) is a unique class of RNA transcribed by RNA polymerase II …

MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma

D Li, X Liu, L Lin, J Hou, N Li, C Wang, P Wang… - Journal of Biological …, 2011 - ASBMB
In our in-depth analysis carried out by the Illumina Solexa massive parallel signature
sequencing, microRNA-99a (miR-99a) was found to be the sixth abundant microRNA in the …

SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs

R Bartoszewski, M Dabrowski… - … of Physiology-Lung …, 2020 - journals.physiology.org
Cold viruses have generally been considered fairly innocuous until the appearance of the
severe acute respiratory coronavirus 2 (SARS-CoV-2) in 2019, which caused the …

MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing

Y Jin, SD Tymen, D Chen, ZJ Fang, Y Zhao, D Dragas… - PloS one, 2013 - journals.plos.org
Recent studies suggest that microRNAs play important roles in dermal wound healing and
microRNA deregulation has been linked with impaired wound repair. Here, using a mouse …

MicroRNA profiling in prostate cancer-the diagnostic potential of urinary miR-205 and miR-214

A Srivastava, H Goldberger, A Dimtchev, M Ramalinga… - PloS one, 2013 - journals.plos.org
Prostate cancer (PCa) is the most common type of cancer in men in the United States, which
disproportionately affects African American descents. While metastasis is the most common …

MicroRNAs in the ionizing radiation response and in radiotherapy

C Metheetrairut, FJ Slack - Current opinion in genetics & development, 2013 - Elsevier
Radiotherapy is a form of cancer treatment that utilizes the ability of ionizing radiation to
induce cell inactivation and cell death, generally via inflicting DNA double-strand breaks …