In both type 1 and type 2 diabetes, the late diabetic complications in nerve, vascular
endothelium, and kidney arise from chronic elevations of glucose and possibly other …

The retina was first described by Herophilus of Chalcedon around 300 bc. It was named by
Rufos of Ephesus (c. 110 ad) and appeared to early anatomists as a surrounding net which …

Diabetic retinopathy (DR) is one of the most common microvascular complications of
diabetes and is the leading cause of blindness in young adults. Oxidative stress has been …

The growing number of people with diabetes worldwide suggests that diabetic retinopathy
(DR) and diabetic macular edema (DME) will continue to be sight threatening factors. The …

Oxidative stress is a term used to denote the imbalance between the concentrations of
reactive oxygen and nitrogen species and the defense mechanisms of the body. Although it …

Diabetes is known to involve oxidative stress and changes in lipid metabolism. Many
secondary plant metabolites have been shown to possess antioxidant activities, improving …

We examined the ability of pyridoxamine (PM), an inhibitor of formation of advanced
glycation end products (AGEs) and lipoxidation end products (ALEs), to protect against …

α-Lipoic acid (LA) is a disulfide compound that is produced in small quantities in cells, and
functions naturally as a co-enzyme in the pyruvate dehydrogenase and α-ketoglutarate …

Background: Oxidative stress has been implicated in the major complications of diabetes
mellitus, including retinopathy, nephropathy, neuropathy and accelerated coronary artery …

Results: The red cell MDA levels were significantly higher in all types of diabetes compared
to age-matched normal controls. The mean of red cell MDA level was highest in type 2 DM …