[HTML][HTML] Circulating tumor DNA as liquid biopsy in lung cancer: Biological characteristics and clinical integration

C Li, J Shao, P Li, J Feng, J Li, C Wang - Cancer Letters, 2023 - Elsevier
Lung cancer maintains a high morbidity and mortality rate globally despite significant
advancements in detection and therapy in the era of precision medicine. Excisional biopsy …

Identification and Application of Emerging Biomarkers in Treatment of Non-Small-Cell Lung Cancer: Systematic Review

JC Restrepo, D Martínez Guevara, A Pareja López… - Cancers, 2024 - mdpi.com
Simple Summary Lung cancer remains a leading cause of cancer-related mortality globally,
requiring new diagnostic and therapeutic approaches. This research arises from the need to …

A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs

J Xie, B Hu, Y Gong, S He, J Lin, Q Huang… - Journal of Translational …, 2023 - Springer
Background Liquid biopsy provides a non-invasive approach that enables detecting
circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) using blood specimens …

LIBELULE: a randomized phase III study to evaluate the clinical relevance of early liquid biopsy in patients with suspicious metastatic lung cancer

A Swalduz, C Schiffler, H Curcio, B Ambasager… - Journal of Thoracic …, 2024 - Elsevier
Purpose Genomic profiling is a major component for first-line treatment decisions in patients
with non-small cell lung cancer (NSCLC) and the timeliness of biomarker testing is essential …

'Plasma first'approach for detecting epidermal growth factor receptor mutation in advanced non-small cell lung carcinoma

A Rathor, PS Malik, P Tanwar, S Khurana… - Journal of Cancer …, 2024 - Springer
Introduction The treatment approach for recently diagnosed advanced non-small cell lung
cancer (NSCLC) with EGFR mutations primarily relies on confirming the tissue diagnosis as …

Agnostic drug development revisited

A Hernando-Calvo, A Rossi, M Vieito, E Voest… - Cancer Treatment …, 2024 - Elsevier
The advent of molecular profiling and the generalization of next generation sequencing in
oncology has enabled the identification of patients who could benefit from targeted agents …

Promise and Perils of Precision Oncology for Patients With Pediatric and Young Adult Sarcomas

AJ Church, CE Wakefield, K Hetherington… - American Society of …, 2024 - ascopubs.org
The completion of multiple national pediatric precision oncology platform trials and the
incorporation of standardized molecular profiling into the diagnostic care of pediatric and …

[HTML][HTML] Liquid and Tissue Biopsies for Lung Cancer: Algorithms and Perspectives

P Hofman - Cancers, 2024 - mdpi.com
Simple Summary A liquid biopsy (LB) is now considered to be a valuable diagnostic tool for
advanced and metastatic nonsquamous nonsmall cell lung cancer (NS-NSCLC) patients …

Circulating Tumor DNA in Genitourinary Cancers: Detection, Prognostics, and Therapeutic Implications

MB Gerke, CS Jansen, MA Bilen - Cancers, 2024 - mdpi.com
Simple Summary Circulating tumor DNA (ctDNA) is a non-invasive method of identifying and
monitoring genitourinary cancers, including prostate, bladder, and renal cell carcinoma, via …

Overview of the Role of Liquid Biopsy in Non-small Cell Lung Cancer (NSCLC)

AV Ospina - Clinical Oncology, 2024 - Elsevier
Solid tumour tissue has traditionally been used for cancer molecular diagnostics. Recently,
biomarker assessment in blood or liquid biopsies has become relevant because it allows …