Preimplantation genetic diagnosis/screening (PGD/PGS) aims to help couples lower the
risks of transmitting genetic defects to their offspring, implantation failure, and/or miscarriage …

Purpose Balanced carriers of structural rearrangements have an increased risk of
unbalanced embryos mainly due to the production of unbalanced gametes during meiosis …

Conventional PCR methods combined with linkage analysis based on short tandem repeats
(STRs) or Karyomapping with single nucleotide polymorphism (SNP) arrays, have been …

Many factors may affect the chances for successful pregnancy, especially at a later age.
Fertility evaluations including genetic analysis are recommended to couples that have not …

Research question Can preimplantation genetic testing (PGT) with next-generation
sequencing (NGS) increase the chance of achieving a balanced euploid pregnancy in …

Hearing loss may place a heavy burden on the patient and patient's family. Given the high
incidence of hearing loss among newborns and the huge cost of treatment and care …

Research question Is there a simple and effective method for male patients with genetic
disorders in families with no identified haplotype and with Robertsonian translocations to …

Objectives The present study attempted to confirm a method that distinguishes a balanced
Robertsonian translocation carrier embryo from a truly normal embryo in parallel with …

This study provides an overview of preimplantation genetic diagnosis (PGD) for single gene
diseases and the management of expanding indications in the context of a fully financially …

Las translocaciones robertsonianas se producen por la fusión de los brazos largos de dos
cromosomas acrocéntricos y son frecuentes en los seres humanos. Sin embargo, su …